Table 1.
Subject Demographic and baseline characteristics of the study volunteers.
| Demographic data | Baseline | ECa 233, 250 mg | ECa 233, 500 mg |
|---|---|---|---|
| Gender, % (n) | |||
| Female | 50% (n = 6) | 45.5% (n = 5) | |
| Male | 50% (n = 6) | 54.5% (n = 6) | |
| Agea (year) | 26 [9.5] | 26.5 [9.25] | |
| Body mass indexb (kg/m2) | 21.49 ± 1.66 | 21.37 ± 1.70 | 20.95 ± 1.58 |
| Systolic blood pressureb (mmHg) | 110 ± 10 | 117 ± 7 | 115 ± 11 |
| Diastolic blood pressureb (mmHg) | 65 ± 11 | 64 ± 6 | 59 ± 5 |
| Body temperature (°C) | 36.6 ± 0.4 | 36.3 ± 0.6 | 37.0 ± 0.1 |
| Clinical laboratory screeningb | |||
| White blood cell (× 103/µL) | 6.58 ± 0.89 | 6.11 ± 1.29 | 6.74 ± 1.91 |
| Red blood cell (× 106/µL) | 5.05 ± 0.31 | 4.84 ± 0.29 | 4.83 ± 0.42 |
| Hemoglobin (g/dL) | 13.6 ± 1.9 | 13.0 ± 1.7 | 13.0 ± 2.1 |
| Platelet (× 103/µL) | 307 ± 69 | 299 ± 77 | 317 ± 85 |
| Fasting blood glucose (mg/dL) | 84.58 ± 3.99 | 87.25 ± 6.28 | 89.55 ± 6.42 |
| Blood urea nitrogen (mg/dL) | 13 ± 3 | 12 ± 4 | 11 ± 4 |
| Creatinine (mg/dL) | 0.72 ± 0.19 | 0.73 ± 0.20 | 0.79 ± 0.21 |
| Albumin (g/dL) | 4.48 ± 0.26 | 4.58 ± 0.23 | 4.45 ± 0.27 |
| Total bilirubin (mg/dL) | 0.70 ± 0.42 | 0.68 ± 0.37 | 0.60 ± 0.30 |
| AST (U/L) | 18 ± 5 | 23 ± 15 | 19 ± 5 |
| ALT (U/L) | 18 ± 9 | 19 ± 9 | 20 ± 14 |
| Alkaline phosphatase (U/L) | 52 ± 9 | 52 ± 9 | 52 ± 9 |
| Total cholesterol (mg/dL) | 173 ± 25 | 174 ± 21 | 172 ± 25 |
| Triglycerides (mg/dL) | 76 ± 46 | 77 ± 34 | 77 ± 48 |
| HDL cholesterol (mg/dL) | 55 ± 8 | 57 ± 8 | 56 ± 8 |
| LDL cholesterol (mg/dL, calculated) | 104 ± 22 | 101 ± 20 | 100 ± 24 |
| Sodium (mmol/L) | 137 ± 1 | 137 ± 1 | 138 ± 1 |
| Chloride (mmol/L) | 105 ± 2 | 107 ± 2 | 105 ± 2 |
| Potassium (mmol/L) | 3.9 ± 0.3 | 3.9 ± 0.3 | 4.2 ± 0.3 |
| Calcium (mg/dL) | 9.5 ± 0.4 | 9.7 ± 0.3 | 9.5 ± 0.4 |
| Magnesium (mg/dL) | 2.5 ± 0.1 | 2.4 ± 0.1 | 2.4 ± 0.2 |
| Phosphorus (mg/dL) | 3.5 ± 0.4 | 3.9 ± 0.5 | 3.9 ± 0.4 |
Decimal numbers were reported according to laboratory standard of Maha Chakri Sirindhorn Clinical Research Center, Faculty of Medicine, Chulalongkorn University.
AST aspartate aminotransferase, ALT alanine aminotransferase, HDL high-density lipoprotein, LDL low-density lipoprotein.
aData is expressed as median [IQR].
bData are expressed as mean ± SD, (n = 11–12).