Table 2.
Predictors of baseline gametocyte density among infections containing gametocytes in the school cohort.
Predictor | N gametocyte positive | Bivariate associations* | Multivariable associations* | ||
---|---|---|---|---|---|
% Difference** [95% CI] | p-value | % Difference [95% CI] | p-value | ||
Site/schoola | |||||
Bvumbwe | 19 | Ref | 0.36 | Ref | 0.20 |
Ngowe | 24 | − 39 [− 93 to 470] | − 50 [− 89 to 123] | ||
Maseya | 71 | − 63 [− 95 to 170] | − 37 [− 81 to 108] | ||
Makhuwira | 65 | − 79 [− 97 to 70] | − 70 [− 91 to 1] | ||
Season | |||||
Dry | 77 | Ref | < 0.001 | Ref | < 0.001 |
Rainy | 102 | 4740 [2210 to 10040] | 5186 [2447 to 10870] | ||
Age (per year increase) | 179 | − 12 [− 29 to 10] | 0.25 | − 18 [− 30 to − 3] | 0.02 |
Sex | |||||
Male | 92 | Ref | 0.12 | ||
Female | 87 | 150 [− 20 to 710] | |||
Hemoglobin | |||||
Not anemic | 137 | Ref | 0.42 | ||
Anemicb | 41 | 80 [− 58 to 670] | |||
Fever statusc | |||||
Afebrile | 78 | Ref | 0.13 | ||
Febrile | 101 | 120 [− 20 to 510] | |||
Recent treatmentd | |||||
Not treated | 168 | Ref | 0.21 | ||
Treated | 10 | 340 [− 56 to 4240] | |||
Slept under a nete | |||||
No | 102 | Ref | 0.30 | ||
Yes | 73 | 90 [− 43 to 510] |
*Obtained in a survey weighted (weights calculated by school*standard) linear regression with logarithm transformed gametocyte density as an outcome, and analyzing the variables shown in the table.
**Percent difference in gametocyte density from reference category is calculated as: [exp(coeff) − 1] × 100.
OR = Odds Ratio; CI = Confidence Interval. Bold values are statistically significant for p-values < 0.05.
aUnivariate association for school, all bivariate include adjustment for school.
bHemoglobin < 11.0 g/dL; 1 missing observation.
cMeasured temperature ≥ 37.5 °C at baseline visit or reported in the last two weeks.
dReported in the last two weeks; 1 missing observations.
e4 missing observations.