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. 2021 Mar 25;11:6905. doi: 10.1038/s41598-021-86450-5

Table 2.

Predictors of baseline gametocyte density among infections containing gametocytes in the school cohort.

Predictor N gametocyte positive Bivariate associations* Multivariable associations*
% Difference** [95% CI] p-value % Difference [95% CI] p-value
Site/schoola
Bvumbwe 19 Ref 0.36 Ref 0.20
Ngowe 24  − 39 [− 93 to 470]  − 50 [− 89 to 123]
Maseya 71  − 63 [− 95 to 170]  − 37 [− 81 to 108]
Makhuwira 65  − 79 [− 97 to 70]  − 70 [− 91 to 1]
Season
Dry 77 Ref  < 0.001 Ref  < 0.001
Rainy 102 4740 [2210 to 10040] 5186 [2447 to 10870]
Age (per year increase) 179  − 12 [− 29 to 10] 0.25  − 18 [− 30 to − 3] 0.02
Sex
Male 92 Ref 0.12
Female 87 150 [− 20 to 710]
Hemoglobin
Not anemic 137 Ref 0.42
Anemicb 41 80 [− 58 to 670]
Fever statusc
Afebrile 78 Ref 0.13
Febrile 101 120 [− 20 to 510]
Recent treatmentd
Not treated 168 Ref 0.21
Treated 10 340 [− 56 to 4240]
Slept under a nete
No 102 Ref 0.30
Yes 73 90 [− 43 to 510]

*Obtained in a survey weighted (weights calculated by school*standard) linear regression with logarithm transformed gametocyte density as an outcome, and analyzing the variables shown in the table.

**Percent difference in gametocyte density from reference category is calculated as: [exp(coeff) − 1] × 100.

OR = Odds Ratio; CI = Confidence Interval. Bold values are statistically significant for p-values < 0.05.

aUnivariate association for school, all bivariate include adjustment for school.

bHemoglobin < 11.0 g/dL; 1 missing observation.

cMeasured temperature ≥ 37.5 °C at baseline visit or reported in the last two weeks.

dReported in the last two weeks; 1 missing observations.

e4 missing observations.