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. 2021 Mar 12;12:647864. doi: 10.3389/fendo.2021.647864

Table 1.

List of the 10 single nucleotide polymorphism considered in the genetic risk score computation.

Reported gene SNP Functional class Alleles MAF (%) Mexicans MAF (%) 1000 GP (37) OR 95% CI p Reference
SLC16A11 rs13342232 synonymous A/G 41.6 16.3 1.9 1.2-3.0 0.003 (26)
ADORA1 rs903361 intergenic A/G 27.8 37.7 1.9 1.2-3.0 0.010 (27)
CADM2 rs13078807 intron A/G 9.3 8.7 2.2 1.2-4.0 0.009 (27)
GNPDA2 rs10938397 intergenic A/G 32.5 32.6 2.2 1.4-3.7 9.0E-4 (27)
VEGFA rs6905288 downstream G/A 35.5 35.5 1.4 1.1-2.1 0.044 (27)
FTO rs9939609 intron T/A 20.6 34.0 1.8 1.0-2.3 0.039 (27)
POC5 rs2112347 upstream G/T 29.6 48.9 1.7 1.4-2.1 6.9E-4 (23)
RPS10 rs206936 intron A/G 34.6 35.5 1.5 1.2-1.8 0.005 (23)
GLIS3 rs7034200 intron A/C 35.5 44.4 2.1 1.8-2.4 1.9E-6 (23)
LINGO rs10968576 intron A/G 21.2 20.4 2.0 1.6-2.4 4.3E-4 (23)

SNP, single nucleotide polymorphism; MAF, minor allele frequency; 1000 GP, 1000 genome project; OR, odds ratio; CI, confidence interval.