Table 3.

Logistic regression for pediatric-onset type 2 diabetes using clinical risk factors and the genetic risk score as predictors.

	OR	95% CI	p
Model 1 (pseudo R2 = 0.15, p < 0.001)*
BMI (Z-score)	1.7	1.1 ; 2.5	0.009
Maternal Diabetes	7.1	2.8 ; 17.8	<0.001
Age (years)	1.1	0.9 ; 1.2	0.444
Gender (male)	1.1	0.6 ; 2.3	0.72
Fitness score	0.9	0.9 ; 1.0	0.822
Model 2 (pseudo R2 = 0.14, p < 0.001)
GRS (per risk allele)	1.3	1.1 ; 1.6	0.006
Model 3 (pseudo R2 = 0.21), p < 0.001)*
GRS (per risk allele)	1.3	1.0 ; 1.6	0.025
BMI (Z-score)	1.5	0.9 ; 2.4	0.146
Maternal Diabetes	8.5	2.8 ; 26.1	<0.001
Age (years)	1.1	0.9 ; 1.3	0.332
Gender (male)	1.2	0.5 ; 2.9	0.75
Fitness score	1.0	1.0 ; 1.0	0.778

*McFadden’s pseudo R², likelihood ratio p < 0.001.

OR, odds ratio; CI, confidence interval.