Table 2.
Case demographics.
| HC (n = 8) | DS (n = 12)* | AD (n = 10) | p-value | Group-wise comparisons (p-value) | |
|---|---|---|---|---|---|
| Age (years) | 70.88 ± 12.55 [51–85]a | 51.00 ± 6.41 [44–60] | 81.70 ± 7.97 [71–98] | <0.001b | DS < HC (0.011) DS < AD (<0.001) |
| Male/Female (n) | 3/5 | 4/8 | 3/7 | 0.9c | — |
| PMI (h) | 13.88 ± 5.41 [3–20]a | 7.48 ± 5.58 [2.2–20] | 5.20 ± 1.18 [3.5–6] | 0.029b | AD < HC (0.037) |
| Brain weight (g)** | 1259.40 ± 70.73 [1180–1400]a | 954.40 ± 121.92 [700–1090] | 1108.50 ± 177.00 [925–1430] | 0.003b | DS < HC (0.002) |
| Braak scores (n)*** | I [1], II [2], III [1], IV [3], V [1] | V [3], VI [9] | V [2], VI [7] | ≤0.001b | HC < AD, DS (≤0.001) |
Dementia DS n = 9; non-dementia DS n = 3.
**
1 dementia DS subject and 1 non-dementia DS subject do not have brain weight data.
***
1 AD subject does not have a Braak score.
a
Mean ± SD [range].
b
Kruskal–Wallis test.
c
Chi-squared.