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. 2021 Jan 13;31(5):e2211. doi: 10.1002/rmv.2211

FIGURE 1.

FIGURE 1

Viral entry, dissemination and damage to various organs. Severe acute respiratory syndrome coronavirus 2 virus initially infects respiratory system. If not controlled, it could enter the circulation system and subsequently infect various organs such as heart, liver, kidney, brain and intestines. The virus may also initially gain entry into the digestive system, and could disseminate to other organs. The damage to major organs can cause severe consequences such as acute respiratory distress syndrome, microvascular thrombosis, disseminated intravascular coagulation, acute heart failure, liver dysfunction, acute kidney injury/kidney failure, encephalitis/stroke and intestinal inflammation