Table 2.
Projected number of recurrent stroke events over a five-year follow-up time horizon for a calculated 2018 patent foramen ovale closure candidate pool of patients with prior ischaemic stroke, no closure versus closure treatment, and resulting numbers needed to treat.
| All prior ischaemic stroke candidates treated without PFO closure | All prior ischaemic stroke candidates treated with PFO closure | Absolute risk difference | Number needed to treat | |
|---|---|---|---|---|
|
Estimated number of recurrent stroke events over five years, based on epidemiological stroke incidence data |
||||
| England | 415 | 133 | 282 | 14 |
| France | 503 | 161 | 342 | |
| Germany | 590 | 189 | 401 | |
| Italy | 274 | 88 | 186 | |
|
Estimated number of recurrent stroke events over five years, based on administrative stroke incidence data |
||||
| England | 953 | 305 | 648 | 14 |
| France | 675 | 216 | 459 | |
| Germany | 1482 | 474 | 1008 | |
| Italy | 265 | 85 | 180 | |
PFO: patent foramen ovale.
Top: based on epidemiological stroke incidence data; bottom: based on administrative stroke incidence data.