TABLE 2.
Mean levels and SDs of coagulation variables in whole blood at different sampling times (T0, T35) and in fresh frozen plasma at 1 year of storage
| LR WB | nLR WB | P a | FFP | |||||
|---|---|---|---|---|---|---|---|---|
| Parameter (laboratory reference range) | T0 | T35 | T0 | T35 | LR vs nLR | T0 vs T35 | T0 |
P for the comparisons with all combinations between type of bags and sampling time |
| PT (5.4‐7.8 seconds) | 9.38 (1.45) | 10.64 (1.82) | 9.28 (1.51) | 11.66 (2.87) | ns | <.001 | 9.57 (1.45) | ns |
| aPTT (9.4‐15.6 seconds) | 19.22 (4.42) | 20.26 (2.13) | 13.74 (0.91) | 15.52 (2.13) | .036 | .031 | 17.01 (2.62) | P = .02 with nLR at T0 |
| Fibrinogen (108‐416 mg/dL) | 141.60 (17.4) | 125.00 (19.4) | 145.80 (16.27) | 134.40 (19.78) | <.001 | <.001 | 135.44 (46.24) | ns |
| FVII (62%‐150%) | 62.40 (15.63) | 53.20 (15.74) | 62.40 (17.01) | 54.80 (13.26) | ns | <.001 | 55.33 (13.3) | ns |
| FVIII (60%‐135%) | 72.20 (14.97) | 42.00 (11.11) | 84.00 (14.28) | 52.40 (17.83) | ns | <.001 | 59.23 (24.38) | ns |
| FIX (55%‐110%) | 60.00 (11.51) | 46.80 (6.14) | 66.20 (11.37) | 53.60 (7.73) | .024 | <.001 | 52.33 (9.48) | ns |
| FXI (50%‐110%) | 61.50 (34.20) | 52.20 (40.22) | 93.25 (17.63) | 83.40 (10.85) | na | na | 63.59 (8.18) | na |
| FXII (60%‐125%) | 89.00 (26.87) | 78.40 (15.29) | 102.25 (16.88) | 89.40 (14.94) | na | na | 76.52 (10.68) | na |
Note: na indicates statistical analyses not performed due to the reduced number of observations and high observed variability.
Abbreviations: aPTT, activated partial thromboplastin time; FFP, fresh frozen plasma; LR, leukoreduced; nLR, non‐leukoreduced; PT, prothrombin time; WB, whole blood.
a
For all parameters, no significant interaction between type of bags and sampling time. Mean values between nLR WB and LR WB.