Fig. 2.

Fibrosing nonspecific interstitial pneumonia in a 43-year-old woman with interstitial pneumonia with autoimmune features (IPAF; fluorescent antinuclear antibody [FANA], 1:640).

(a, b) Lung window images of CT scans obtained at levels of right interior pulmonary vein (a) and liver dome (b), respectively, show reticular lesions and traction bronchiolectasis (arrowhead in b) in bilateral subpleural lungs.

(c) Low-power magnification of lung obtained from right lower lobe by VATS demonstrates mild pleural fibrosis, and airway centered fibrosis containing lymphoid aggregates including some with germinal centers. Although not specific, lymphoid follicles with germinal centers are often associated with connective tissue disease.