Fig. 3.

Interstitial lung abnormality combined with lung adenocarcinoma in a 71-year-old man.

(a, b) Lung window images of CT scans obtained at levels of right interior pulmonary vein (a) and liver dome (b), respectively, show subpleural reticular lesions mixed with some ground-glass opacity in both lungs. Also note a 26-mm-sized nodule in right lower lobe. Inset in a: high fluorodeoxyglucose uptake within nodule at positron emission tomography indicating malignant nature of nodule.

(c) Low-power magnification of lung obtained from a right lower lobectomy demonstrates focal subpleural fibrosis with cystic spaces and anthracosis. Histologically similar images shown by Miller et al⁶⁴ and Hung et al⁶⁵ were classified as UIP.