Fig. 4.

Interstitial lung abnormality and mucin-producing lung adenocarcinoma in a 73-year-old man.

(a, b) Lung window images of CT scans obtained at levels of suprahepatic inferior vena cava (a) and liver dome (b), respectively, show reticular lesions and traction bronchiolectasis (arrowheads) in both lungs. Also note a 23-mm-sized lung nodule in left lung base. Inset: rather mild fluorodeoxyglucose uptake within nodule at positron emission tomography indicating mucin-producing nature of lung cancer.

(c) Low-power magnification of lung obtained from a left lower lobe lobectomy demonstrates focal subpleural fibrosis (arrows) with cystic spaces (open arrows). These histologic findings do not meet pathologic criteria for the diagnosis of UIP or fibrosing NSIP.