Table 2.

Histologic Diagnosis and HRCT Features of Idiopathic Non-specific Interstitial Pneumonia.

Histologic Features
Cellular Pattern
Mild to moderate interstitial chronic inflammation
Type II pneuocyte hyperplasia in areas of inflammation
Fibrosing Pattern
Dense or loose interstitial fibrosis with uniform appearance
Frequent lung architectural preservation
Mild or moderate chronic interstitial inflammation

HRCT Findings
Bilateral symmetric and predominantly lower lung zone involvement
Reticular opacity with traction bronchiectasis and lower lobe volume loss
Diffuse or subpleural in axial planes; sometimes spare subpleural lungs
Based on American Thoracic Society Project for idiopathic nonspecific interstitial pneumonia (Travis WD et al; reference #40)