TABLE 3.
Semi‐quantitative evaluation of the H.E.‐stained liver slices: Semi‐quantitative eval‐uation of the liver slices, shown representatively in Figure 5, was performed according to the method described by Koppe et al., 2004. [20]
| Control | NFD +Solvent | HFD +Solvent | UDCA (40.0) + HFD | I‐ol (0.4) + HFD | I‐ol (4.0) + HFD | I‐ol (40.0) + HFD | I‐an (0.4) + HFD | I‐an (4.0) + HFD | I‐an (40.0) + HFD | |
|---|---|---|---|---|---|---|---|---|---|---|
| Steatosisa | 0 | 0 | 1 | 0–1 | 0–1 | 0 | 0–1 | 0–1 | 0–1 | 0–1 |
| Balooninga | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0–1 | 1 | 0–1 |
| Inflammation b | 0 | 0 | 2 | 1 | 1–2 | 1 | 1 | 1 | 1 | 1 |
Steatosis and ballooning: 0, none; 1, ≤25%; 2, 26–50%; 3, ≥51–75% of liver parenchyma.
b
Inflammation: 0, none; 1, <5 signs of inflammation; 2, >5 signs of inflammation in the microscopic field at 40x magnification.