Table 2.

Transfusion frequency in three subtypes of necrotizing enterocolitis.

	Combined cohort (N = 336)	Medical non-fulminant NEC (N = 138)	Surgical non-fulminant NEC (N = 163)	Fulminant NEC (N = 35)	P1 Ful vs. SNF	P2 Ful vs. MNF	P3 SNF vs. MNF
Platelet transfusion before NEC	n = 226	n = 56	n = 152	n = 18
Number of platelet transfusion, n (%)					0.319	0.337	0.892
0	192 (85.0%)	48 (85.7%)	130 (85.5%)	14 (77.8%)
1	17 (7.52%)	5 (8.93%)	11 (7.24%)	1 (5.56%)
2	8 (3.54%)	1 (1.79%)	6 (3.95%)	1 (5.56%)
3+	9 (3.98%)	2 (3.57%)	5 (3.29%)	2 (11.1%)
Platelet transfusion after 48 h	n = 226	n = 53	n = 154	n = 19
Number of platelet transfusion, n (%)					0.373	0.002	<0.001
0	149 (65.9%)	48 (90.6%)	90 (58.4%)	11 (57.9%)
1	46 (20.4%)	3 (5.66%)	36 (23.4%)	7 (36.8%)
2	17 (7.52%)	1 (1.89%)	16 (10.4%)	0 (0.00%)
3+	14 (6.19%)	1 (1.89%)	12 (7.79%)	1 (5.26%)
RBC transfusion before NEC	n = 296	n = 122	n = 143	n = 31
Number of RBC transfusion, n (%)					0.392	0.335	0.246
0	155 (52.4%)	67 (54.9%)	71 (49.7%)	17 (54.8%)
1	29 (9.80%)	12 (9.84%)	12 (8.39%)	5 (16.1%)
2	35 (11.8%)	9 (7.38%)	22 (15.4%)	4 (12.9%)
3+	77 (26.0%)	34 (27.9%)	38 (26.6%)	5 (16.1%)
RBC transfusion after 48 h NEC	n = 281	n = 113	n = 137	n = 31
Number of RBC transfusion, n (%)					0.574	<0.001	<0.001
0	117 (41.6%)	79 (69.9%)	31 (22.6%)	7 (22.6%)
1	91 (32.4%)	29 (25.7%)	48 (35.0%)	14 (45.2%)
2	40 (14.2%)	4 (3.54%)	32 (23.4%)	4 (12.9%)
3+	33 (11.7%)	1 (0.88%)	26 (19.0%)	6 (19.4%)

Data represented as n (%); differences in categorical measures tested using the Chi-squared test or Fisher’s exact test; P1 = Fulminant vs. surgical non-fulminant (SNF), P2 = fulminant (ful) vs. medical non-fulminant (MNF), P3 = MNF vs. SNF, p < 0.05 significant.

Statistically significant p < 0.05 values are in bold.

NEC necrotizing enterocolitis, RBC red blood cell.