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. 2021 Mar 26;41(5):1110–1121. doi: 10.1038/s41372-021-01044-3

Table 5.

Transfusion and mortality.

ALL Combined group Discharged
Death Discharged p value ALL MNF NEC SNF NEC p value
N = 321 N = 85 N = 236 N = 236 N = 114 N = 122
Platelet tx before NEC n = 225 n = 62 n = 163 n = 163 n = 51 n = 112
 Platelet tx before NEC 0.09 0.832
  0 191 (84.9%) 47 (75.8%) 144 (88.3%) 144 (88.3%) 44 (86.3%) 100 (89.3%)
  1 17 (7.56%) 7 (11.3%) 10 (6.13%) 10 (6.13%) 4 (7.84%) 6 (5.36%)
  2 8 (3.56%) 4 (6.45%) 4 (2.45%) 4 (2.45%) 1 (1.96%) 3 (2.68%)
  3+ 9 (4.00%) 4 (6.45%) 5 (3.07%) 5 (3.07%) 2 (3.92%) 3 (2.68%)
  Total yes 34 (15.1%) 15 (24.2%) 19 (11.7%) 19 (11.7%) 7 (13.7%) 12 (10.7%)
Platelet tx 48 h after NEC n = 225 n = 63 n = 162 n = 162 n = 47 n = 115
 Platelet tx 48 h after NEC 0.99 <0.001
  0 148 (65.8%) 42 (66.7%) 106 (65.4%) 106 (65.4%) 43 (91.5%) 63 (54.8%)
  1 46 (20.4%) 13 (20.6%) 33 (20.4%) 33 (20.4%) 3 (6.38%) 30 (26.1%)
  2 17 (7.56%) 4 (6.35%) 13 (8.02%) 13 (8.02%) 1 (2.13%) 12 (10.4%)
  3+ 14 (6.22%) 4 (6.35%) 10 (6.17%) 10 (6.17%) 0 (0.00%) 10 (8.70%)
  Total yes 77 (34.2%) 21 (33.3%) 56 (34.6%) 56 (34.6%) 4 (8.51%) 52 (45.2%)
Blood tx before NEC n = 282 n = 73 n = 209 n = 209 n = 100 n = 109
 Blood tx before NEC 0.823 0.036
  0 147 (52.1%) 35 (47.9%) 112 (53.6%) 112 (53.6%) 56 (56.0%) 56 (51.4%)
  1 27 (9.57%) 8 (11.0%) 19 (9.09%) 19 (9.09%) 9 (9.00%) 10 (9.17%)
  2 32 (11.3%) 8 (11.0%) 24 (11.5%) 24 (11.5%) 5 (5.00%) 19 (17.4%)
  3+ 76 (27.0%) 22 (30.1%) 54 (25.8%) 54 (25.8%) 30 (30.0%) 24 (22.0%)
  Total yes 135 (47.9%) 38 (52.1%) 97 (46.4%) 97 (46.4%) 44 (44.0%) 53 (48.6%)
Blood tx before NEC n = 267 n = 73 n = 194 n = 194 n = 91 n = 103
 Blood tx 48 h after NEC 0.003 <0.001
  0 108 (40.4%) 17 (23.3%) 91 (46.9%) 91 (46.9%) 66 (72.5%) 25 (24.3%)
  1 89 (33.3%) 28 (38.4%) 61 (31.4%) 61 (31.4%) 22 (24.2%) 39 (37.9%)
  2 37 (13.9%) 16 (21.9%) 21 (10.8%) 21 (10.8%) 2 (2.20%) 19 (18.4%)
  3+ 33 (12.4%) 12 (16.4%) 21 (10.8%) 21 (10.8%) 1 (1.10%) 20 (19.4%)
  Total yes 159 (59.6%) 56 (76.7%) 103 (53.1%) 103 (53.1%) 25 (27.5%) 78 (75.7%)

Cells are represented as n (%), differences in categorical measures were tested using a chi-square test or Fisher’s exact test.

MNF medical non-fulminant NEC, SNF surgical non-fulminant NEC.