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Selpercatinib safety overview
| TRAEs with selpercatinib (LOXO-292) |
LIBRETTO-001 Safety Database* (N = 531) |
|
|---|---|---|
| Any | Grade 3 | |
| Dry mouth | 27 | – |
| Diarrhea | 16 | 1 |
| Hypertension | 18 | 8 |
| AST increased | 22 | 4 |
| ALT increased | 21 | 6 |
| Fatigue | 14 | < 1 |
| Constipation | 11 | < 1 |
| Headache | 7 | < 1 |
| Nausea | 8 | < 1 |
| Peripheral edema | 10 | – |
| Creatinine increased | 10 | – |
TRAEs, Treatment related adverse events
*Includes all tumor types (eg, NSCLC, MTC, Thyroid, etc.)
