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. 2021 Mar 26;19:126. doi: 10.1186/s12967-021-02792-8

Table 2.

The type and frequency of PRDX gene family neighbor gene alterations in hepatocellular carcinoma (cBioPortal)

Genes Amplification Homozygous deletion Up-regulation Down-regulation Mutation Total alteration
AR 0.069 0 0.028 0.094
CDK1 0.006 0.064 0 0 0.069
EPX
GPX1
GSS
GSTP1 0.025 0.025 0 0.006 0.053
KLK3 0.008 0.036 0 0 0.044
LCK 0.003 0.006 0.033 0 0.011 0.053
LPO
MAPK1 0.003 0.003 0.047 0.069 0.008 0.131
MAX 0.003 0.053 0.058 0 0.111
MYC 0.178 0.003 0 0 0.006 0.186
PBK 0.058 0.053 0 0.003 0.114
PRDX1 0.003 0.064 0.003 0.003 0.072
PRDX2 0.003 0.081 0.003 0.006 0.092
PRDX3 0.003 0.05 0.053 0.006 0.111
PRDX4
PRDX5 0.003 0.083 0 0 0.086
PRDX6 0.097 0.089 0 0.003 0.175
PXDN
STK4 0.003 0.05 0 0.003 0.056
TXN 0.003 0.058 0 0.003 0.061
TXN2 0.008 0.083 0.008 0.008 0.106
TXNDC12
TXNRD1 0.008 0.072 0 0 0.081
TXNRD2 0.006 0.003 0.047 0 0 0.056
TXNRD3