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. 2021 Mar 25;13:65. doi: 10.1186/s13195-021-00805-8

Table 2.

Correlations (rho) of plasma NfL and plasma p-tau181 levels with other biomarkers

Plasma NfL Plasma p-tau181
rho p-value rho p-value
CN participants
 CSF Aβ1–42 0.130 0.235 − 0.021 0.849
 CSF Aβ1–42/1–40 −0.074 0.510 − 0.0173 0.128
 CSF p-tau181 0.242 0.026 0.326 0.003
 CSF tau 0.26 0.016 0.213 0.055
 Plasma NfL 0.317 < 0.001
 Plasma p-tau181 0.317 < 0.001
 Hippocampal volume 0.027 0.817 0.023 0.849
CI participants
 CSF Aβ1–42 −0.052 0.584 0.415 < 0.001
 CSF Aβ1–42/Aβ1–40 −0.006 0.950 − 0.328 < 0.001
 CSF p-tau181 0.148 0.116 0.417 < 0.001
 CSF tau 0.233 0.013 0.496 < 0.001
 Plasma NfL 0.336 < 0.001
 Plasma p-tau181 0.336 < 0.001
 Hippocampal volume − 0.349 0.002 −0.135 0.235