B. longum PI10 strain and B. animalis subsp. lactis LA804 and L. gasseri LA806 mixture had an impact on the HFD-induced microbiota dysbiosis. (A) Relative abundance of the dominant phyla evaluated by 16S rRNA MiSeq sequencing in cecal contents. (B) Relative abundance of Actinobacteria for each group of mice. (C) PCoA (Unifrac) analysis showing comparative differences between groups at the phylum, family, and genus levels. (D) Diversity indexes (observed, Shannon, Simpson). (E) Differences in the relative abundance of families between groups. (F) Differences in the relative abundance of families and (G) genera between LFD and HFD groups. (H) Differences in the relative abundance of families and (I) genera between HFD and HFD-PI10 groups. (J) Differences in the relative abundance of families and (K) genera between HFD and HFD-LA804 + LA806 groups. * p < 0.05, ** p < 0.01; *** p < 0.001.