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. 2021 Feb 24;12(3):323. doi: 10.3390/genes12030323
ADP Adenosine-5′-diphosphate
AITD Autoimmune thyroid disease
cDNA Complementary DNA
CRISPR/Cas9 RGENs Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) systems. CRISPR/Cas systems can be modified and redirected to become powerful tools for genome editing in many species.
CTLA4 Cytotoxic T-lymphocyte-associated protein 4
DMT1 Diabetes mellitus type 1
DNA Deoxyribonucleic acid
DOCK8 Dedicator of cytokinesis 8
DSB DNA double-strand break
ETS Erythroblast transformation-specific (family of transcription factors)
FKH domain Forkhead domain
FOXP3 Forkhead box P3
GAD antibodies Glutamic acid decarboxylase antibodies
GITR Glucocorticoid-induced TNFR-related protein (belongs to the tumor necrosis factor receptor superfamily (TNFRSF))
HAAs Antiharmonin autoantibodies
HLA system Human leukocyte antigen system
HSCT Hematopoietic stem cell transplantation
IA2 antibodies Tyrosine phosphatase-related islet antigen 2
IgE Immunoglobulin E
IgG Immunoglobulin G
IgM Immunoglobulin M
IL2RA Interleukin 2 receptor α chain (also called CD25)
IL2RG Interleukin 2 Receptor Subunit γ
IL4 Interleukin 4
IPEX syndrome Immune dysregulation, polyendocinopathy, enteropathy, X-linked syndrome
LRBA Lipopolysaccharide (LPS)-responsive and beige-like anchor protein
LZ leucine zipper
mncRNAs Micro-noncoding ribonucleic acids
mRNA Messenger RNA
ncRNAs Noncoding ribonucleic acids
NFAT Nuclear factor of activated T cells
PBMC Peripheral blood mononuclear cell
PRR N-terminal proline-rich region
PTPN22 Protein tyrosine phosphatase, non-receptor type 22
RORγ Retinoic acid-related orphan receptor γ (master activator of cholesterol biosynthesis)
RUNX Runt-related transcription factors
SCID-XI Severe combined immunodeficiency
STAT1 Signal transducer and activator of transcription 1
STAT3 Signal transducer and activator of transcription 3
STAT5b Signal transducer and activator of transcription 5B
Tconv cells Conventional T cells that differentiate into effector cells during immune responses
TG Ab Thyroglobulin antibody
TGF Transforming growth factor
TNFRSF18 Tumor necrosis factor receptor superfamily member 18 (known as GITR)
TPO Ab Thyroperoxodase antibody
Treg Regulatory T cell
TTC37 Tetratricopeptide repeat domain 37
TTC7A Tetratricopeptide repeat domain 7A
VAAs Antivillin autoantibodies
WT-FOXP3 Wild-type FOXP3
XCI X-chromosome inactivation
ZF Central zinc finger
ZnT8 antibodies Zinc transporter 8 antibodies