TABLE 1.
Variable | Summary (N = 585) |
---|---|
Age at death (years) | 79 (50, 99) |
Sex (men) | 345 (59.0%) |
Braak NFT stage | |
0 | 13 (2.2%) |
I | 20 (3.4%) |
II | 99 (16.9%) |
III | 148 (25.3%) |
IV | 92 (15.7%) |
V | 94 (16.1%) |
VI | 119 (20.3%) |
Thal amyloid phase | |
0 | 61 (11.2%) |
1 | 51 (9.4%) |
2 | 27 (5.0%) |
3 | 112 (20.6%) |
4 | 46 (8.4%) |
5 | 248 (45.5%) |
LBD subtype | |
Brainstem | 72 (12.3%) |
Transitional | 208 (35.6%) |
Diffuse | 305 (52.1%) |
Lewy body counts | |
Middle frontal gyrus | 3 (0, 35) |
Superior temporal gyrus | 7 (0, 50) |
Inferior parietal gyrus | 2 (0, 30) |
Cingulate gyrus | 8 (0, 35) |
Parahippocampal gyrus | 14 (0, 45) |
Putaminal TH-ir | |
Dorsolateral | 4.26 (0.26, 42.18) |
Ventromedial | 9.99 (0.26, 39.18) |
Substantia nigra neuronal loss score | |
Ventrolateral | |
0 = none | 3 (0.6%) |
0.5 = none/mild | 10 (2.1%) |
1 = mild | 56 (11.8%) |
1.5 = mild/moderate | 55 (11.6%) |
2 = moderate | 61 (12.9%) |
2.5 = moderate/severe | 55 (11.6%) |
3 = severe | 233 (49.3%) |
Medial | |
0 = none | 24 (5.4%) |
0.5 = none/mild | 26 (5.8%) |
1 = mild | 83 (18.6%) |
1.5 = mild/moderate | 53 (11.9%) |
2 = moderate | 56 (12.6%) |
2.5 = moderate/severe | 54 (12.1%) |
3 = severe | 150 (33.6%) |
The sample median (minimum, maximum) is given for continuous variables. Information was unavailable for Thal amyloid phase (N = 40), Lewy body counts in the middle frontal (N = 20), superior temporal (N = 21), inferior parietal (N = 21), cingulate (N = 27), and parahippocampal (N = 88) gyri, dorsolateral putaminal TH-ir (N = 107), ventromedial putaminal TH-ir (N = 107), ventrolateral SN neuronal loss score (N = 112), and medial SN neuronal loss score (N = 139).