TABLE 5.

Multivariate analysis for serum CA19-9 response and Margin

Variables	Disease-free Survival			Survival
CA19-9 Response ≥85% & R0	1			1
CA19-9 Response <85% & R0	1.518	1.014, 2.271	0.042	1.690	0.993, 2.878	0.053
CA19-9 Response ≥85% & R1	1.775	0.835, 3.771	0.136	2.047	1.010, 4.148	0.047
CA19-9 Response <85% & R1	2.638	1.537, 4.531	<0.0001	2.619	1.032, 6.649	0.043
BMI (Kg/m2)				0.955	0.916, 0.996	0.032
Pre-operative Albumin (g/dL)	0.649	0.464, 0.908	0.012	0.581	0.401, 0.841	0.004
Vein resection	1.467	1.046, 2.058	0.026	1.329	0.899, 1.965	0.153
T-size (cm)				1.252	1.009, 1.554	0.041
Positive Nodes (N1)	1.616	1.124, 2.325	0.010	1.137	0.973, 1.330	0.107
Number of Positive Nodes				1.078	1.036, 1.122	<0.0001
Adjuvant Chemotherapy				0.549	0.363, 0.830	0.004

Abbreviations: BMI: body mass index (in Kg/m²); T-size: pathologic tumor size; N1: any positive lymph nodes.