. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: Urol Oncol. 2020 Jul 12;38(12):932.e1–932.e7. doi: 10.1016/j.urolonc.2020.06.015

Table 3.

Genes located in the region of gain at cytoband 18q21.31 presenting in exclusively MET outcome samples.

Gene	Function	Association with cancer	Association with CaP
MALT1	Paracaspase-Forms complex to activate NF-kB	-First identified in B-cell Lymphoma²⁸ -Upregulated in Breast and Lung^20,22	Increase associated with lower survival long-term^16,17
NEDD4L	E3 ubiquitin Ligase	Downregulated in Colon Cancer¹⁴	N/A
ALPK2	Kinase Negative regulator of WNT signaling in cardiogenesis²⁷	Downregulated in Colon Cancer⁵	N/A
miRNA-122	Highly expressed in Liver	Downregulated in Liver Cancer²⁹	Upregulated in high Gleason cancer¹⁵