Table 6. Comparative analysis of Final MHC I, MHC II and B cell epitopes.
| S. no | Protein name | Start | B cell epitopes (IFNscore) | Cross-reactivity with human | START | MHC I epitopes (IFNscore) | Cross-reactivity with human | Start | MHC II Epitopes (IFNscore) | Cross-reactivity with human |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ORF8 protein | 15 | PYVVDDPCPIHFYSKW(1) | NO | 10 | CTQHQPYVVDDPCPI(1) | NO | |||
| 2 | Envelope protein | 23 | YSRVKNLNSSRVP(−0.49) | NO | ||||||
| 3 | ORF3a protein | 15 | LKQGEIKDATPSDFVR(0.62) | NO | 4 | MRIFTIGTV(−0.43) | NO | |||
| 4 | Surface glycoprotein | 55 | VSGTNGTKRF(−0.75) | NO | 242 | WTAGAAAYY(0.57) | NO | 98 | KTQSLLIVNNATNVV(−0.37) | NO |
| 123 | DPFLGVYYHKNNKSWMESEFRVYSSA(3.7) | NO | 498 | LSFELLHAPATVCGP(−0.51) | NO | |||||
| 234 | LTPGDSSSGWTA(−0.14) | NO | – | – | – | – | – | – | ||
| 641 | VNNSYECDIPI(1) | NO | – | – | – | – | – | – | ||
| 680 | YTMSLGAENSVAYSNN(−0.04) | NO | – | – | – | – | – | |||
| 792 | PDPSKPSKR(0.12) | NO | – | – | – | – | – | – | ||
| 477 | LQSYGFQPTNGVGYQP(14) | NO | ||||||||
| 391 | EVRQIAPGQTGKIADY(1) | NO | ||||||||
| 1114 | VIGIVNNTVYDPLQPE(12) | NO | ||||||||
| 5 | Orf1ab polyprotein | 365 | VVKIYCPACHNSEVGP(2) | NO | 3841 | LSDDAVVCF(−0.30) | NO | 20 | KSAFYILPSIISNEK(0.33) | NO |
| 771 | SEAVEAPLVGTPVCIN(2) | NO | 2413 | VVTTFDSEY(−0.51) | NO | 1801 | ESPFVMMSAPPAQYE(−0.21) | NO | ||
| 2242 | SSEIIGYKAIDGGVTR(2) | NO | 295 | FMGRIRSVY(−0.25) | NO | 2390 | QMEIDFLELAMDEFI(0.31) | NO | ||
| 813 | FTLKGGAP(−0.22) | NO | 4615 | LQAENVTGL(−0.21) | NO | 2755 | NYIFWRNTNPIQLSS(−0.27) | NO | ||
| 1482 | AVTAYNGYLTSSSKTPEE(−0.04) | NO | 2166 | NYMPYFFTL(−0.58) | NO | 663 | QMNLKYAISAKNRAR(1) | NO | ||
| 3072 | GCSCDQLREPMLQSADAQS(0.41) | NO | 5406 | FELEDFIPM(−0.28) | NO |