Table 8. Molecular docking of vaccine construct with different TLRs and HLA alleles.
S. no. | Receptor | Receptor PDB | Global Energy |
---|---|---|---|
1 | TLR4 | 2Z62 | −1.64 |
3UL8 | 2.16 | ||
2Z63 | −28.76 | ||
3UL9 | −1.43 | ||
2Z65 | −18.55 | ||
2Z66 | −23.62 | ||
3FXI | −6.93 | ||
3ULA | −1.75 | ||
4G8A | −2.65 | ||
5NAM | −6.18 | ||
2Z64 | 1.23 | ||
2 | TLR1-2 hetero dimer | 2Z81 | −0.88 |
2Z80 | −31.20 | ||
2Z82 | 0.22 | ||
2Z7X | 3.75 | ||
3 | TLR1 | 6NIH | −1.95 |
1FYV | −6.49 | ||
4 | TLR2 | 6NIG | 10.81 |
5 | TLR6 | 3A79 | −13.05 |
6 | TLR3 | 2A0Z | −8.85 |
1ZIW | 6.11 | ||
7 | HLA Alleles | 5IM7 | −24.66 |
1XR8 | −1.95 | ||
1SYS | −17 | ||
1A6A | −5.59 | ||
1A1M | −3.24 | ||
1BX2 | 6.09 | ||
1H15 | −9.32 | ||
1ZSD | 5.51 | ||
3C5J | 5.12 | ||
4O2E | 9.68 |