Table 3.

Methodological index for nonrandomized studies (MINORS) to assess the methodological quality and risk of bias of the observational included studies. The items are scored 0 (not reported), 1 (reported but inadequate) or 2 (reported and adequate). The global ideal score being 16 for noncomparative studies and 24 for comparative studies.

Methodological Index for Nonrandomized Studies (MINORS)
AUTHORS	Clearly stated aim	Inclusion of consecutive patients	Prospective collection of data	Endpoints appropriate to the aim of the study	Unbiased assessment of the study endpoint	Follow-up period appropriate to the aim of the study	Loss to follow up less than 5%	Prospective calculation of the study size	Adequate control group	Contemporary groups	Baseline equivalence of groups	Adequate statistical analyses	OUTCOME
Boer et al. (2019) [25]	2	2	2	2	0	0	2	2	1	2	1	2	18
Huang et al. (2016) [26]	2	2	2	2	0	0	2	2	0	0	0	2	14