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. 2021 Feb 25;12(3):336. doi: 10.3390/genes12030336

Figure 1.

Figure 1

Geographical distribution of three ATP7B prevalent pathogenic variants (p.R778L, p.P992L, p.T935M) in Chinese mainland: (a) the geographical distribution of 709 Wilson’s disease (WD) patients. Various colors in different regions indicate the corresponding number range of patients; (bd) the frequency of p.R778L, p.P992L and p.T935M in five regions (Fujian, Zhejiang, Jiangsu, Shanghai and Jiangxi). Five regions are represented by different colors. Asterisks indicate that there existed significant differences between the corresponding two provinces (** p < 0.01).