Table 1.

Effects of AMG on extracellular signal-regulated kinases (ERK) and myelin basic protein (MBP) levels in PPA-treated autistic rats.

Groups	ERK (ng/mL)	R-MBP (µg/mL)
Vehicle Control	100.5 ± 0.85	100.3 ± 0.82
Sham Control	100.7 ± 0.58	100.7 ± 0.54
AMG200 per se	100.6 ± 0.61	100.7 ± 0.59
PPA	250.7 ± 0.51 *	152.9 ± 0.55 *
PPA + AMG100	210.4 ± 0.53 @	145.5 ± 0.60 @
PPA + AMG200	190 ± 0.59 @#	130.7 ± 0.59 @#

Statistical analysis followed by one-way ANOVA (post-hoc Tukey’s test), * p < 0.05 v/s vehicle control; sham control and AMG200 per se; ^@ p < 0.05 v/s PPA; ^@# p < 0.05 v/s PPA + AMG100; (n = 6 rats per group).