Skip to main content
. 2021 Feb 25;11(3):288. doi: 10.3390/brainsci11030288

Table 4.

Effects of AMG on the evaluation of inflammatory cytokines level in PPA-treated autistic rats.

Groups Neuroinflammatory Markers
TNF-α
(pg/mg Protein)		 IL-1β
(pg/mg Protein)
Vehicle Control 28.83 ± 0.84 12.48 ± 0.54
Sham Control 28.93 ± 0.85 12.56 ± 0.79
AMG200 per se 28.41 ± 0.57 12.62 ± 0.68
PPA 66.93 ± 0.99 * 25.90 ± 0.37 *
PPA + AMG100 60.29 ± 0.58 @ 20.93 ± 0.37 @
PPA + AMG200 48.37 ± 0.50 @# 16.82 ± 0.33 @#

Statistical analysis followed by one-way ANOVA (post-hoc Tukey’s test), * p < 0.05 v/s vehicle control; sham control and AMG200 per se; @ p < 0.05 v/s PPA; @# p < 0.05 v/s PPA + AMG100; (n = 6 rats per group).