Figure 2.

A summary of the different roles of H3K56Ac: H3K56Ac has been implicated in a variety of processes, related both to replication and to genome stability. Of these processes, evidence exists that ties H3K56Ac to homologous recombination repair pathways, in particular strand invasion and break induced repair (BIR). In addition, there is an effect on mismatch repair, expansions and contractions in the number of trinucleotide repeats, maintenance of origin-less chromosomal segments, and the prevention of chromosomal abnormalities such as mutations and rearrangements. H3K56Ac is also connected to replication, and to firing of origins and cell cycle progression. See text for more details.