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. 2021 Feb 25;9(3):478. doi: 10.3390/microorganisms9030478

Figure 2.

Figure 2

Phage cross activities (lytic abilities) of the 22 newly isolated phages against 32 Pseudomonas aeruginosa (PA) isolates (Pa_Ph1–Pa_Ph32) from patients with cystic fibrosis (CF); (n) = numbers. Phages are stratified in (A), and CF PA isolates in (B) according to the various lung infection stages: Black for first infection (i.e., CF PA isolated right after the first infection); light grey, early infection (i.e., early CF PA isolated one year after the first infection); grey, chronic non-mucoid CF PA isolates, and very light grey, chronic mucoid CF PA isolates (i.e., chronic CF PA isolated for at least five years after first infection). Overall, whereas all the newly isolated environmental phages showed the same lytic activity against several first CF PA infections, phages (Φ16_-Φ22_OBG) isolated from the Bambino Gesù (OBG) sewage source showed lytic ability against 20 or more CF PA isolates tested, and the best lytic activity against chronic non-mucoid or mucoid CF PA isolates (A,B).