Figure 2.

Clinical and biochemical features involved in disease symptom severity in SARS-CoV-2 infected subjects. Above, the role of primary factors of risk (clinical features: age, diabetes, cardiovascular diseases, and obesity [111,112,113,114,125,150]) for severe disease are shown. Below, other factors (biochemical features: levels of vitamin D, statins, interferon activity, and G6PD [132,133,134,138,140,145]) that are suggested to be involved in COVID-19 severity are summarised. Abbreviations: G6PD, glucose-6-phosphate dehydrogenase. The figure was created with Biorender.com.