Table 3.
Antibiotic Use Rate Multivariable Generalized Linear Model Analysis
| Characteristic | Model 1a | Model 2a | ||||
|---|---|---|---|---|---|---|
| Coefficient | (95% CI) | P Value | Coefficient | (95% CI) | P Value | |
| GA categoryb, wk | ||||||
| 28–31 | –0.31 | (–.37 to –.26) | < .001 | 0.07 | (.002–.14) | .04 |
| 32–34 | 0.05 | (–.01 to .10) | .08 | 0.59 | (.52–.65) | < .001 |
| Male sexc | 0.10 | (.06–.14) | < .001 | 0.09 | (.05–.13) | < .001 |
| Race/ethnicityd | ||||||
| African American | 0.23 | (.17–.29) | < .001 | 0.22 | (.16–.29) | < .001 |
| Hispanic | 0.30 | (.24–.35) | < .001 | 0.26 | (.20–.32) | < .001 |
| Asian/other/unknown | 0.14 | (.09–.18) | < .001 | 0.15 | (.10–.20) | < .001 |
| Birth yeare | ||||||
| 2011 | –0.04 | (–.10 to .02) | .15 | –0.05 | (–.11 to .02) | .16 |
| 2012 | –0.10 | (–.16 to –.04) | .001 | –0.11 | (–.18 to –.05) | .001 |
| 2013 | –0.05 | (–.11 to .02) | .15 | –0.07 | (–.14 to –.002) | .06 |
| 2014 | –0.15 | (–.22 to –.07) | < .001 | –0.13 | (–2.0 to –.05) | .001 |
| 2015 | –0.15 | (–.23 to –.06) | .001 | –0.18 | (–.27 to –.09) | < .001 |
| 2016 | –0.27 | (–.37 to –.17) | < .001 | –0.30 | (–.40 to –.19) | < .001 |
Abbreviations: CI, confidence interval; GA, completed gestational age.
aModel 1 includes all infants (N = 17 836). Model 2 includes only surviving infants without bacterial sepsis or necrotizing enterocolitis (n = 15 924).
bReference = GA 23–27 weeks.
cReference = Female sex.
dReference = White race/ethnicity.
eReference = 2010.