Figure 1.
The creatine transporter. The creatine transporter (green) shuttles creatine from the extracellular space into the cytoplasm of the cell and is comprised of 12 transmembrane domains. Creatine kinase catalyzes a reversible reaction between creatine and phosphocreatine, resulting in the generation of ATP. NH2 = amine terminus, COOH = carboxy terminus.