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. 2021 Feb 26;13(3):305. doi: 10.3390/pharmaceutics13030305

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effect of zein hybridization in PC-NP on the photocytotoxicity of encapsulated ICG. Each ICG formulation was used for treatment on the day of preparation (A) or after a four-day storage at room temperature (B). PC-NP and Z/PC-NP were prepared from 21.8 mg of lipid (DMPC:CHOL mixture) and 14.8 mg of lipid and 7 mg of zein mixture, respectively. Significant differences between treatments without irradiation or with irradiation are indicated by asterisks: * p < 0.05; ** p < 0.01; *** p < 0. 001.