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. 2021 Feb 26;9(3):45. doi: 10.3390/toxics9030045

Figure 2.

Figure 2

Predicted dissociation constant (KD) values (geometric mean ± 1 standard error) for different peroxisome proliferator-activated receptors (PPAR)–per- and polyfluorinated alkyl substances (PFAS) complexes. (A) PPAR-α and perfluoroalkyl carboxylates (PFCAs) (B) PPAR-α and perfluoroalkyl sulfonates (PFSAs) (C) PPAR-γ and PFCAs (D) PPAR-γ and PFSAs (E) PPAR-δ and PFCAs (F) PPAR-δ and PFSAs. Values of log KD > 3 correspond to millimolar or weaker binding, between −3 and 3 are moderate (in the micromolar range) and < −3 correspond to strong, nanomolar, or lower binding.