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Dissociation constant (KD) values ± SE measured by equilibrium dialysis.
| Protein | PFAS | KD (µM) |
|---|---|---|
| L-FABP | PFHxA | ND |
| PFOA | 0.099 ± 0.015 | |
| PFBS | ND | |
| PFHxS | 1.7 ± 0.031 | |
| PFOS | 0.18 ± 0.032 | |
| I-FABP | PFHpA | ND |
| PFNA | ND | |
| PPAR-α | PFBA | ND |
| PFHxA | 0.097 ± 0.070 | |
| PFHpA | ND | |
| PFNA | 0.083 ± 0.028 | |
| PPAR-γ | PFOA | 0.057 ± 0.027 |
| PFOS | 8.5 ± 0.46 | |
| PPAR-δ | PFBA | 0.044 ± 0.013 |
| PFBS | ND | |
| PFHxS | 0.035 ± 0.0020 | |
| PFOS | 0.69 ± 0.33 |
“ND”: no dissociation constant could be determined, indicating low to no binding.
