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. 2021 Feb 27;11(3):361. doi: 10.3390/biom11030361

Table 1.

Physical and chemical properties of α-, β- and γ-cyclodextrin (CD).

Property α-CD β-CD γ-CD
Glucopyranose units 6 7 8
Molecular weight (Da) 972 1135 1297
Solubility in water (mg/mL) 145 18.5 232
Inner diameter (Å) 5.7 7.8 9.5
Safety (orally) High * Acceptable daily intake of 5 mg/kg/day High *
Chemical structure graphic file with name biomolecules-11-00361-i001.jpg graphic file with name biomolecules-11-00361-i002.jpg graphic file with name biomolecules-11-00361-i003.jpg

* According to the Regulatory Status of Cyclodextrins, they can be taken without restrictions [21].