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Representative confocal images of MDA-MB231 and BALB/3T3 cells exposed to HNPs (0.1 mg mL−1) for 24 h. CD44 receptors were blocked with free hyaluronic acid (HA) (10 equivalents of HNPs concentration) 1 h before treatment with HNPs. Green, blue, and red fluorescence correspond to fluorescein isothiocyanate (FITC)-HNPs, cell nuclei and cytoskeleton, respectively. Cells exposed to culture medium were used as the negative control. Scale bar: 50 µm.
