Table 1.
Sensitivity and specificity of findings differentiating pulmonary edema from pulmonary fibrosis in interstitial lung disease (ILD). PLA—pleural line abnormalities, B to Z—Conversion of B-line artifacts to Z-line (with the frequency changed from 2 MHz to 6 MHz), *—single examination zone; SE—sensitivity, SP—specificity, PPV—positive predictive value, NPV—negative predictive value, LR(+)—positive likelihood ratio, LR(−)—negative likelihood ratio, AUC—area under the curve, AIC—Akaike information criterion, OR—odds ratio, CI—confidence interval.
| Finding | SE (%) | SP (%) | PPV (%) | NPV (%) | LR(+) | LR(−) | AUC | p-Value | AIC | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|---|---|
| PLA * | 68 | 99 | 99 | 68 | 60 | 0.32 | 0.836 | 0.0002 | 510.8 | 184.08 (57.79–586.28) |
| B to Z * | 61 | 76 | 80 | 55 | 2.58 | 0.51 | 0.687 | 0.03 | 779.8 | 5.03 (3.54–7.15) |
| model A | 44 | 97 | 93 | 62 | 13.13 | 0.58 | 0.702 | 0.035 | 73.91 | 22.56 (2.73–186.47) |
| model B | 91 | 97 | 97 | 91 | 27.19 | 0.097 | 0.936 | 7 × 10−6 | 32.68 | 280.33 (27.52–2855.45) |
| model C | 91 | 73 | 78 | 88 | 3.40 | 0.13 | 0.820 | 0.0012 | 60.98 | 26.58 (6.31–111.97) |