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Intravital bioluminescence and fluorescence microscope configuration. (a) Photograph of microscope: charge-coupled device (CCD) camera on the right port, confocal system on the left port, yellow box indicates filter wheel, green arrow indicates black box placed over animal, and red arrow and red box show the manual shutter. (b) Quantification of light leakage throughout the system at every level of light elimination displayed with log scale (GL, grey level); **** p < 0.0001
