Table 6. Statistical analysis of migraineurs persistence towards treatment using chi-square and Cox proportional hazard regression analysis.
| Risk factors | Cox Regression Analysis | ||
|---|---|---|---|
| P-value | HR3 | CI4 (95%) | |
| Migraineurs | |||
| Low Frequency | 0.0002 | –– | |
| High frequency | <0.0001 | 1.628 | (1.221–2.179) |
| Chronic | 0.0002 | 0.881 | (0.762–0.912) |
| Age | <0.0001 | 1.293 | (1.092–1.458) |
| Patients with depression | <0.0001 | 1.268 | (1.084–1.458) |
| Epilepticus seizures | 0.0002 | 0.922 | (0.654–1.206) |
| Patients with other comorbidities | 0.0003 | 0.671 | (0.352–1.011) |
| Class of drugs | |||
| NSAIDs | <0.0001 | –– | |
| Combination analgesics | 0.0004 | 1.817 | (0.841–2.725) |
| Triptans | 0.0005 | 0.701 | (0.182–1.414) |
| Triptans + NSAIDs | <0.0001 | 0.758 | (0.501–1.289) |
| Prophylaxis drugs | <0.0001 | 1.314 | (0.958–1.424) |
1Continuers, 2Discontinuer
3Hazard Ratio
4Confidence interval, p<0.0001
*Figures in parentheses indicate the reference category of categorical variables (hazard ratio = 1), hazard ratio is adjusted for other variables in the table.
*Data of patients who drop-out during the study period or didn’t experienced event during whole study period were censored in survival analysis.