Table 2. Correlation between factors and postoperative CSF leakage.
| Intraop CSF leakage | Postop CSF leakage | Rate (%) | p value | odd ratio | |
|---|---|---|---|---|---|
| Gender | 0.438 | 1.457 | |||
| Male | 115 | 8 | 7.0 | ||
| Female | 145 | 13 | 9.0 | ||
| Age (yr) | 50.4 ± 15.6 | 50.3 ± 15.7 | 0.4 | 1.013 | |
| Surgery | |||||
| Primary | 193 | 11 | 5.7 | 0.017* | 0.345 |
| Revision | 67 | 10 | 14.9 | 0.017* | 2.903 |
| Repair surgery of postop CSF leakage | 21 | 6 | 28.6 | 0.003* | 5.973 |
| Pathology | |||||
| Pituitary adenoma | 188 | 8 | 4.3 | < 0.001* | 0.202 |
| Rathke’s cleft cyst | 17 | 1 | 5.9 | 1 | 0.697 |
| Craniopharyngioma | 25 | 9 | 36.0 | < 0.001* | 10.453 |
| Meningioma | 10 | 3 | 30.0 | 0.576 | 1.278 |
| Chordoma | 9 | 0 | 0.0 | 1 | 0.962 |
| Chondrosarcoma | 1 | 0 | 0.0 | 1 | 0.992 |
| Arachnoid cyst | 1 | 0 | 0.0 | 1 | 0.992 |
| Others | 9 | 2 | 22.2 | 0.159 | 3.489 |
| CSF leak Grade | |||||
| Grade 1 | 135 | 6 | 4.4 | 0.025* | 0.341 |
| Grade 2 | 83 | 7 | 8.4 | 0.885 | 1.072 |
| Grade 3 | 42 | 8 | 19.0 | 0.01* | 3.71 |
| Material of reconstruction | |||||
| Buttress | 178 | 12 | 6.7 | 0.232 | 0.578 |
| Fat | 108 | 5 | 4.6 | 0.086 | 0.413 |
| SDS | 91 | 10 | 11.0 | 0.206 | 1.773 |
| Pedicled vasculized flap | 105 | 12 | 11.4 | 0.12 | 2.021 |
| Nasoseptal flap | 94 | 11 | 11.7 | 0.106 | 2.067 |
| Middle turbinate flap | 11 | 1 | 9.1 | 1 | 1.145 |
*P<0.05 for the test.
SDS, synthetic dural substitute.