Supplemental Figure 2.
mRNA-1273 (Moderna/NIH) induces a greater IgA response than does BNT 162b2 (Pfizer/BioNTech)
A–C, Violin plots show the log10 transformed mean fluorescence intensity (MFI) for (A) IgA spike–, (B) IgG spike–, and (C) IgM spike–specific titers across V1 and V2 time points collected from nonpregnant (blue), pregnant (orange), or lactating (purple) participants receiving either mRNA-1273 (Moderna) or BNT 162b2 (Pfizer). Differences across time points and groups were assessed by repeated measures mixed-effects model followed by post hoc Tukey’s multiple comparisons test. The dotted line depicts PBS background level. The asterisk indicates P<.05, the double asterisk indicates P<.01, the triple asterisk indicates P<.001, the quadruple asterisk indicates P<.0001.
Ig, immunoglobulin; mRNA, messenger RNA; NIH, National Institutes of Health; PBS, phosphate-buffer saline.
Gray et al. Coronavirus disease 2019 vaccination in pregnancy and lactation. Am J Obstet Gynecol 2021.