Table 2.
Characteristics of pregnant, delivered vaccine recipients and lactating vaccine recipients
| Pregnant, delivered vaccine recipients (n=13) | |
|---|---|
| Characteristic | |
| Gestational age at delivery, median (IQR), wk | 39.3 (39–40.3) |
| Days from the first vaccine to delivery, median (IQR) | 36.5 (30–42) |
| Days from the second vaccine to delivery, median (IQR)a | 14 (11–16) |
| Labor | 11 (85) |
| Mode of delivery | |
| Vaginal | 10 (77) |
| Cesarean | 3 (23) |
| Birthweight, g | 3452 (563) |
| Adverse pregnancy outcome | |
| Fetal growth restriction | 0 (0) |
| Preeclampsia/gestational hypertension | 0 (0) |
| Preterm delivery | 1 (8) |
| - Spontaneous | 1 |
| - Medically indicated | 0 |
| Composite infant morbidityb | |
| Supplemental oxygen/CPAP | 1 (8) |
| TTN | 1 (8) |
| Special care nursery admission | 0 |
| NICU admission | 2 (15) |
| Respiratory distress syndrome | 0 |
| Necrotizing enterocolitis | 0 |
| Sepsis | 0 |
| Assisted ventilation | 0 |
| Seizure | 0 |
| Grade 3/4 intraventricular hemorrhage | 0 |
| Death | 0 |
| Lactating vaccine recipients (n=31) | |
|---|---|
| Characteristic | |
| Months after delivery, median (IQR) | 7.3 (3.8–10.8) |
| Months after delivery | |
| 0–3 | 5 (16) |
| 3–6 | 6 (19) |
| 6–>9 | 18 (58) |
| Unknown | 2 (6) |
Values are expressed as number (percentage) unless indicated otherwise.
CPAP, continuous positive airway pressure; IQR, interquartile range; NICU, neonatal intensive care unit; TTN, transient tachypnea of the newborn.
Gray et al. Coronavirus disease 2019 vaccination in pregnancy and lactation. Am J Obstet Gynecol 2021.
Two patients delivered before receiving the second dose (17 days after V1 and 14 days after V1, cord blood only available for the patient delivering 17 days after V1)
The 1 preterm delivery accounted for the documented cases of supplemental oxygen, TTN, and 1 of the 2 NICU admissions. The other NICU admission was a term infant with growth restriction admitted for persistent hypoglycemia.