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DeepNEU simulations of the calculated 4 component dnCFR as a measure of SARS-CoV-2 infectivity. A, calculated 4 component dnCFR measure for LOF mutations. B, calculated 4 component dnCFR measure for GOF mutations. dnCFR is the DeepNEU measure of SAR-CoV-2 infectivity, where (-4) represents the maximum reduction in viral infectivity and (+4) represents the maximum increase in infectivity. Results are from 3 separate experiments ± 95% CI.
