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. 2020 Feb 11;92(5):4053–4064. doi: 10.1021/acs.analchem.9b05658

Table 1. A Summary of the Figures of Merit Used for Method Characterizationa.

characteristic description FoM interpretation
accuracy closeness of agreement between measurement results and the accepted reference values
graphic file with name ac9b05658_m002.jpg
total prediction error
trueness difference between the expected measurement results and the accepted reference values
graphic file with name ac9b05658_m003.jpg
average of the residuals; systematic component of the total error (i.e., constant offset)
precision closeness of agreement between independent measurement results obtained with the same method in different measurement facilities with different operators using different equipment
graphic file with name ac9b05658_m004.jpg
width of residuals distribution; random component of the total error
a

i and xi are the predicted and assigned reference values, respectively, for the test sample i, and N is the number of samples in the TEST set. Accuracy = reproducibility + trueness (RMSEP2 ≅ SEP2 + BIAS2), as from ISO 5725 (ref (39)).