ADAMTS5 |
A disintegrin-like and metalloproteinase with thrombospondin-1 motifs 5 |
AGO |
Argonaute protein |
AKT |
Serine/threonine-specific protein kinase |
ATG14 |
Autophagy related 14 |
Bcl-2 |
B-cell lymphoma 2 |
BECN1 |
Beclin 1 |
BMI |
Body mass index |
C1, C2, C2C |
Types I and II collagen marker degradation markers |
Camk2d |
Calcium/calmodulin-dependent protein kinase type II delta |
CASPASE-3 |
Cysteine-dependent aspartate-directed proteases 3 |
CBFB |
Core-binding factor subunit beta |
c-miRNA |
Circulating microRNA |
Col2α1 |
The type II collagen gene |
Coll2-1 NO2 |
The nitrated form of α-helical region of type II collagen |
COMP |
Oligomeric matrix protein |
COX2 |
Prostaglandin-endoperoxide synthase 2 |
CPII |
C-propeptide of type II collagen |
CS846 |
Chondroitin sulphate 846 |
CTXI |
C-terminal cross-linked telopeptide of type I collagen |
CTXI alpha and CTXI beta |
Alpha and beta isomerised versions of the CTXI |
CTXII |
C-terminal crosslinked telopeptide of type II collagen |
DMM |
Medical meniscus |
ERG |
Erythroblastosis virus E26 oncogene homolog-related gene |
EZH2 |
Enhancer of zeste homolog 2 |
FGF2 |
Fibroblast growth factor 2 |
FGFR |
Fibroblast growth factor receptor |
HA |
Hyaluronic acid |
HADC2 |
Histone deacetylase 2 |
HDAC4 |
Histone deacetylase 4 |
HDL |
High-density lipoprotein |
HIF-1α |
Hypoxia-inducible factor 1-alpha |
HIF-2α |
Hypoxia-inducible factor 2-alpha |
IGFBP5 |
Insulin-like growth factor-binding protein 5 |
IGFIR |
Insulin-like growth factor 1 receptor |
IGFR |
Insulin-like growth factor 1 receptor |
IL |
Interleukine |
iNOS |
Inducible nitric oxide synthase |
InsR |
Insulin receptor |
IRAK1 |
Interleukin-1 receptor-associated kinase 1 |
LNA-ASO |
Locked nucleic acid antisense oligonucleotide |
LncRNA H19 |
Long non-coding RNA H19 |
MAP1LC3 |
Microtubule-associated proteins 1A/1B light chain 3B |
miRNA |
microRNA |
MMP-13 |
Matrix metalloproteinase 13 |
MMP3 |
Matrix metalloproteinase-3 |
NLRP3 |
The Nacht, leucine-rich repeat and pyrin domain containing protein 3 |
NTXI |
The cross-linked N-telopeptide of type I collagen |
OA |
osteoarthritis |
p16INK4α |
Cyclin dependent kinase inhibitor 2A |
PARP p85 |
Poly (ADP-ribose) polymerase p85 |
PI3K |
Phosphoinositide 3-kinases |
PIIANP |
N-propeptide of collagen IIA |
Ppp3r2 |
Protein phosphatase 3 regulatory subunit B |
PTEN |
Phosphatase and tensin homolog |
qPCR |
Quantitative real-time PCR |
RALA |
Ras-related protein Ral-A |
REGγ |
Langerhans regenerating protein γ |
RUNX2 |
Runt-related transcription factor 2 |
SHIP1 |
Src homology 2 domain containing inositol polyphosphate 5-phosphatase 1 |
SIRT1 |
Sirtuin 1 |
Smad2 |
Mothers against decapentaplegic homolog 2 |
Smad3 |
Mothers against decapentaplegic homolog 3 |
Smad4 |
SMAD family member 4 |
SPP1 |
Secreted phosphoprotein 1 |
TGF |
Transforming growth factor |
TGIF2 |
TGFB-induced factor homeobox 2 |
TIMP2 |
Tissue inhibitor of metalloproteinases 2 |
TRAF3 |
TNF receptor-associated factor 3 |
TRAF6 |
TNF receptor associated factor 6 |
ULK1 |
Unc-51-like autophagy activating kinase 1 |
VEGF |
Vascular endothelial growth factor |
VEGFA |
Vascular endothelial growth factor A |
WISP1 |
Wnt1-inducible signaling pathway protein 1 |