Table 1. Yields of “Double-Binding” Selection of M13 pVIII-12aa and pVIII-12aa-Cys Phage Display Libraries.

	12aa-Cys			12aa
	ina	outb	yieldc	ina	outb	yieldc
round I (against mAbYPF19)	3.5 × 1012	3.3 × 107	9.43 × 10–6	1.5 × 1012	1.3 × 107	8.67 × 10–6
round II (against AD IgGs)	1.45 × 1013	4.2 × 109	2.9 × 10–4	1.7 × 1013	2.65 × 109	1.56 × 10–4
round III (against mAbYPF19)	3.6 × 1012	3.65 × 108	1.01 × 10–4	5.32 × 1012	8.25 × 108	1.55 × 10–4
round IV (against AD IgGs)	8.75 × 1012	2.75 × 109	3.14 × 10–4	1.8 × 1012	1.5 × 109	8.33 × 10–4

^aInput quantity of engineered bacteriophage at the start of the biopanning process.

^bQuantity of phage recovered at the end of each selection round.

^cInput to output ratio to indicate the number of bacteriophage remaining bound to the selection target.