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. 2020 Mar 4;59(6):4002–4014. doi: 10.1021/acs.inorgchem.9b03683

Table 2. IC50 Values (μM) Obtained for Pt Compounds on A431, SVT2, BALB/c-3T3, and HaCaT Cells after 48 h of Incubationa.

cell line 2Pt–Glu 2Pt–Glu–dep 2Pt–Gal 2Pt–OH 1Pt–Glu(11) cisplatin11
HaCaT 43.8 ± 4.3 55 ± 9 >125 13.6 ± 1.6 13 ± 1.7 6.6 ± 0.3
A431 43.8 ± 2.8 41.8 ± 1.7 >125 14.9 ± 0.6 0.40 ± 0.01 39 ± 12
BALB/c-3T3 196 ± 14 59.6 ± 2.6 >125 7.2 ± 0.7 6.3 ± 0.4 240 ± 47
SVT2 176 ± 13 122 ± 5 >125 6.4 ± 0.6 0.65 ± 0.07 195 ± 7
a

The IC50 values for 1Pt–Glu and cisplatin are from ref (11).