Table 2. IC50 Values (μM) Obtained for Pt Compounds on A431, SVT2, BALB/c-3T3, and HaCaT Cells after 48 h of Incubationa.
| cell line | 2Pt–Glu | 2Pt–Glu–dep | 2Pt–Gal | 2Pt–OH | 1Pt–Glu(11) | cisplatin11 |
|---|---|---|---|---|---|---|
| HaCaT | 43.8 ± 4.3 | 55 ± 9 | >125 | 13.6 ± 1.6 | 13 ± 1.7 | 6.6 ± 0.3 |
| A431 | 43.8 ± 2.8 | 41.8 ± 1.7 | >125 | 14.9 ± 0.6 | 0.40 ± 0.01 | 39 ± 12 |
| BALB/c-3T3 | 196 ± 14 | 59.6 ± 2.6 | >125 | 7.2 ± 0.7 | 6.3 ± 0.4 | 240 ± 47 |
| SVT2 | 176 ± 13 | 122 ± 5 | >125 | 6.4 ± 0.6 | 0.65 ± 0.07 | 195 ± 7 |
The IC50 values for 1Pt–Glu and cisplatin are from ref (11).